|
|
|
Your Genes And The Environment You Live
In
What Are "Genes"?
Inside your cells, there are 23 pairs of chromosomes
that carry your genetic information. You received one set
of chromosomes from your mother and one set of chromosomes
from your father. Each chromosome is made up of
two long strands of deoxyribonucleic acid (also known as
DNA). The two strands connect such that the chemical letters,
also known as nucleotides, on each strand pair up. The many
combinations of the four nucleotides in DNA (adenine [A],
thymine [T], guanine [G], and cytosine [C]) spell the language
known as your genetic code.
There are more than six billion nucleotide pairs in your
DNA, some of which accounts for your genes. A gene can be
defined as a sequence of nucleotides that controls one or
more particular characteristics you received from your parents.
Genes influence your physical traits, the likelihood of
suffering from a specific disease or health condition, and
the way your body responds to the environment you live in.
What is a "SNP"?
All humans are similar for 99% of the same
genetic code. So what makes you different from everyone
else? Single nucleotide polymorphisms, or SNPs (pronounced
"Snips") , make up some of these differences.
These are variations in the nucleotides on certain genes.
For example, a portion of your genetic code may be AATGCCAG
while the same portion of your neighbor’s code may
be AATGCCCG. This SNP is one of the things that make you
different from your neighbor. There are over 12 million
SNPs throughout each of our genomes. Scientists have now
developed technology that can use these SNPs to discover
genetic regions that have an effect on the likelihood that
a person will develop a trait or disease.
What Is a "Trait"?
A
trait is a characteristic that is passed down from your
parents through genes. Traits describe characteristics such
as eye color, weight, or the presence or absence of a disease
or condition. One gene or multiple genes can determine what
traits you will have. As an example, your eye color depends
on what genes were passed on to you from your parents and
the combination of SNPs in those genes.
What Does "Environment"
Mean?
While your genes are something inside your
cells that you get from your parents, your environment is
the forces outside your body that affect whether or not
you will develop a particular trait or disease. Simply having
a specific gene does not determine whether or not you will
get a specific trait or disease. There may be environmental
factors that play a role in determining whether or not you
will develop a specific trait or disease. For example, you
may have genes that indicate that you have a high risk of
developing diabetes. However, if you exercise regularly,
keep your weight under control, and make healthy lifestyle
choices, you can effectively control your environment and
reduce your risk for developing diabetes. As a result of
controlling your environment, even if you have the “diabetes
gene,” it is possible that you may never develop diabetes.
How Are Your Genes &
Environment Related to Your Traits?
Together your genes and your environment interact
to determine your traits, or the characteristics that describe
you. The debate surrounding whether genes or the environment
plays a larger role is sometimes referred to as “nature
versus nurture.”
This
concept can be illustrated by thinking about weight. You
may have inherited the gene (or genes) from your parents
that indicate you have a chance of becoming obese. Even
if you are not obese, knowing that you are at a higher risk
of becoming obese may encourage you to talk to your doctor
about preventative measures. Your doctor may discuss healthy
eating habits, exercise routines that are appropriate for
you, or other ways to control your weight. Such preventative
measures may not only decrease your risk of developing obesity,
but they may also decrease your risk of developing other
diseases associated with obesity such as high blood pressure,
diabetes, or heart disease. In this way, the knowledge you
have regarding your genes will allow you to become proactive
about preventing the disease (and possibly other diseases),
thus using your environment to influence your traits.
|
|